Search results for "Cedrus libani"

showing 3 items of 3 documents

Phytochemical and pharmacological properties of essential oils from Cedrus species

2017

Natural products frequently exert pharmacological activities. The present review gives an overview of the ethnobotany, phytochemistry and pharmacology of the Cedrus genus, e.g. cytotoxic, spasmolytic immunomodulatory, antiallergic, anti-inflammatory and analgesic activities. Cancer patients frequently seek remedies from traditional medicinal plants that are believed to exert less side effects than conventional therapy with synthetic drugs. A long-lasting goal of anti-cancer and anti-microbial therapy research is to find compounds with reduced side effects compared to currently approved drugs. In this respect, Cedrus species might be of interest. The essential oil isolated from Cedrus libani…

Antiproliferative activity; Cedrus atlantica; Cedrus deodara; Cedrus libani; essential oils; leukaemia cells; Pinaceae; Analytical Chemistry; Biochemistry; Plant Science; Organic ChemistryCedrus deodaraPhytochemicalsCedrus deodaraCedrus atlanticaAnti-Inflammatory Agentsleukaemia cellsAntiproliferative activityPlant Science01 natural sciencesBiochemistryCedruslaw.inventionNOAnalytical Chemistry03 medical and health sciences0302 clinical medicineAnti-Infective AgentslawOils VolatileHumansMedicinal plantsCedrusessential oilsEssential oilPolycyclic SesquiterpenesCedrus libaniPlants MedicinalTraditional medicinebiologyOrganic ChemistryCedrus libanibiology.organism_classificationPinaceaeAntineoplastic Agents Phytogenic0104 chemical sciencesPlant Leaves010404 medicinal & biomolecular chemistryPhytochemicalDrug development030220 oncology & carcinogenesisCedrus atlanticaSesquiterpenes
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Phytochemical Analysis and Cytotoxicity Towards Multidrug-Resistant Leukemia Cells of Essential Oils Derived from Lebanese Medicinal Plants

2012

Juniperus excelsa fruit essential oil as well as J. oxycedrus, Cedrus libani, and Pinus pinea wood essential oils have been obtained with yields between 2.2 ± 0.3 % to 3.4 ± 0.5 % and analyzed by gas chromatography. Sesquiterpenes mainly characterized C. libani and J. oxycedrus essential oils, while in P. pinea and J. excelsa, monoterpenes were the most abundant compounds. In J. oxycedrus, cis-calamenene (7.8 %), cuparene (3.8 %), and cis-thujopsenal (2.0 %) have been detected for the first time. The cytotoxic activity of these essential oils against drug-sensitive CCRF-CEM and multidrug-resistant P-glycoprotein-expressing CEM/ADR5000 leukemia cells has been investigated (IC₅₀ values: 29.46…

Cupressaceaegas chromatographyPharmaceutical ScienceAnalytical Chemistrylaw.inventionlawDrug DiscoveryTumor Cells CulturedLebanonMedicinal plantsLeukemiabiologyTraditional medicinePinaceaeWoodDrug Resistance MultiplePhytochemicalJuniperus excelsaPinaceaeMolecular MedicineSesquiterpenesJuniperus oxycedruscancer; essential oils; gas chromatography; multidrug resistance; Juniperus excelsa; Juniperus oxycedrus; Cupressaceae; Cedrus libani; Pinus pinea; PinaceaeNOmultidrug resistanceBotanyOils VolatileHumanscancerCedrusessential oilsEssential oilCedrus libaniPharmacologyPlants MedicinalOrganic ChemistryCupressaceaePinusbiology.organism_classificationCedrus libaniAntineoplastic Agents PhytogenicComplementary and alternative medicineDrug Resistance NeoplasmFruitJuniperusMonoterpenesPinus pineaJuniperus excelsaJuniperus oxycedrusPhytotherapyPlanta Medica
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Factors influencing axillary shoot proliferation and adventitious budding in cedar.

2005

We developed procedures for in vitro cloning of Cedrus atlantica Manetti and C. libani A. Rich explants from juvenile and mature plants. Explant size was one determinant of the frequency of axillary bud break in both species. Shoot tips and nodal explants mainly developed calli, whereas bud sprouting occurred in defoliated microcuttings cultured on a modified Murashige and Skoog medium without growth regulators. Isolation and continuous subculture of sprouted buds on the same medium allowed cloning of microcuttings from C. atlantica and C. libani seedlings and bicentennial C. libani trees, thus providing a desirable alternative for multiplying mature trees that have demonstrated superior ch…

chemistry.chemical_classificationBuddingbiologyPhysiologyCedrus atlanticaTemperaturePlant ScienceCedrus libanibiology.organism_classificationPlant RootsTissue Culture TechniquesMurashige and Skoog mediumchemistryPlant Growth RegulatorsAuxinAxillary budShootBotanySeedsCedrusPlant ShootsExplant cultureTree physiology
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